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학술지 논문

  • (2021)  Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation.  Scientific Reports.  11,  1
  • (2020)  Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death.  SCIENCE SIGNALING.  13,  663
  • (2020)  Brain Endothelial P-Glycoprotein Level Is Reduced in Parkinson's Disease via a Vitamin D Receptor-Dependent Pathway.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  21,  22
  • (2020)  Novel Nasal Epithelial Cell Markers of Parkinson's Disease Identified Using Cells Treated with alpha-Synuclein Preformed Fibrils.  JOURNAL OF CLINICAL MEDICINE.  9,  7
  • (2019)  Therapeutic Evaluation of Synthetic Peucedanocoumarin III in an Animal Model of Parkinson's Disease.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  20,  21
  • (2019)  Cell-Based Screen Using Amyloid Mimic beta 23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of alpha-Synuclein and Huntingtin Aggregates.  MOLECULES AND CELLS.  42,  6
  • (2019)  TTC3 contributes to TGF-beta(1)-induced epithelial-mesenchymal transition and myofibroblast differentiation, potentially through SMURF2 ubiquitylation and degradation.  CELL DEATH & DISEASE.  10,  -
  • (2017)  Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models.  ONCOTARGET.  8,  63
  • (2017)  CRISPR-Cas9 Mediated Telomere Removal Leads to Mitochondrial Stress and Protein Aggregation.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  18,  10
  • (2017)  Activation of the ATF2/CREB-PGC-1 alpha pathway by metformin leads to dopaminergic neuroprotection.  ONCOTARGET.  8,  30
  • (2017)  Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson's disease model.  SCIENTIFIC REPORTS.  7, 
  • (2015)  Efficient Mitochondrial Genome Editing by CRISPR/Cas9.  BIOMED RESEARCH INTERNATIONAL. 
  • (2015)  Mitochondrial E3 Ubiquitin Protein Ligase 1 Mediates Cigarette Smoke-Induced Endothelial Cell Death and Dysfunction.  AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY.  54,  2
  • (2012)  Bortezomib Alleviates Experimental Pulmonary Arterial Hypertension.  AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY.  47,  5
  • (2012)  Mesenchymal stem cell-conditioned media recovers lung fibroblasts from cigarette smoke-induced damage.  AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY.  302,  9
  • (2011)  YC-1 attenuates hypoxia-induced pulmonary arterial hypertension in mice.  PULMONARY PHARMACOLOGY & THERAPEUTICS.  24,  6
  • (2011)  Bone marrow cells repair cigarette smoke-induced emphysema in rats.  AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY.  301,  3
  • (2011)  Cigarrette smoke induces AKT degradation by the ubiquitin proteasome system.  JOURNAL OF BIOLOGICAL CHEMISTRY.  286,  37
  • (2011)  Cigarette smoke exacerbates mouse allergic asthma through Smad proteins expressed in mast cells.  RESPIRATORY RESEARCH.  12, 
  • (2010)  Rosiglitazone attenuates hypoxia-induced pulmonary arterial hypertension in rats.  RESPIROLOGY.  15,  4

특허/프로그램

  • 줄기세포 배양액을 포함하는 폐질환 치료용 조성물(Composition for treating pulmonary disease comprising mesenchymal stem cell-conditioned media).  10-1189655-0000.  20121004.  대한민국

학술회의논문

  • (2014)  Cigarette Smoke Extract Induces Tetratricopeptide Repeat Domain 3 Through Retinoic Acid Receptor α and Retinoid X Receptor.  제22회 기초의학 학술대회.  대한민국
  • (2014)  Cigarette Smoke Extract Induces retinoic acid receptor-related orphan receptor alpha (RORα) mediated expression of tetratricopeptide repeat domain 3 (TTC3).  제22회 기초의학 학술대회.  대한민국
  • (2014)  Tetratrico-peptide repeat domain 3 expression is suppressed by Aryl Hydrocarbon Receptor.  제22회 기초의학 학술대회.  대한민국
  • (2014)  Tetratricopeptide Repeat Domain 3 Reciprocally Regulates Cellular Retinoic Acid-Binding Protein 2/Fatty Acid-Binding Protein 5, Mediating Retinoic Acid-Induced Cytotoxicity In Breast Cancer Cells: A Strategy To Overcome Retinoic Acid Resistance.  제22회 기초의학 학술대회.  대한민국
  • (2014)  Cigarette Smoke Extract Induces Expression Of Tetratricopeptide Repeat Domain 3 Through Retinoic Acid Receptor α And Retinoid X Receptor α.  American Thoracid Society International Conference.  미국
  • (2014)  Involvement Of Tetratricopeptide Repeat Domain 3 In Pathophysiology Of Pulmonary Fibrosis.  American Thoracic Society International Conference.  미국
  • (2012)  Mitochondrial ubiquitin ligase activator of NF-κB (MULAN), an Akt Ubiquitin E3 ligase, Mediates Cigarette Smoke-Induced Endothelial Cell Death and Dysfunction.  American Thoracic Society International Congress 2012.  미국
  • (2011)  Cigarette Smoke Causes AKT Degradation Through Ubiquitin Proteasome System In Human Lung Fibroblasts.  Am J Resp Crit Care Med (American Thoracic Society Internation Conference).  미국
  • (2010)  FOXP3+ Treg cells induced by repeated low dose gamma irradiation attenuate OVA-induced mouse allergic inflammation.  제62차 대한약리학회 추계학술대회.  대한민국
  • (2010)  Bortezomib reverses experimental pulmonary hypertension.  제62차 대한약리학회.  대한민국
  • (2010)  Co-culture of astrocytes and mast cells induces bidirectional cross-talks through CD40 and CD40L interaction.  29th Congress of the European Academy of Allergy and Clinical Immunology.  영국
  • (2010)  Signaling pathways in mast cells activated by cross-talk through CD40 and CD40L interaction.  제18회 기초의학학술대회.  대한민국
  • (2010)  Effects of conditioned media of mesenchymal stem cells on lung fibroblasts damaged by cigarette smoke extract.  American Thoracic Society 2010 International Conference.  미국
  • (2009)  Effects of conditioned media of mesenchymal stem cells on lung fibroblasts damaged by cigarette smoke extrct.  제61차 대한약리학회 추계학술대회.  대한민국
  • (2009)  Expressions of Smad Families in Mast Cell Activation Is Correlated to Mouse Allergic Asthma and Regulation of Smad Proteins by Simvastatin.  American journal of Respiratory and Critical Care Medicine.  미국
  • (2009)  Reversal of hypoxia-induced pulmonary arterial hypertension.  American Journal of Respiratory and Critical Care Medicine.  미국
  • (2008)  New therapeutic approaches to treat pulmonary arterial hypertension.  Tuberculosis and respiratory diseases.  대한민국
  • (2008)  New therapeutic approaches to treat pulmonary arterial hypertension.  제60차 대한약리학회 추계학술대회.  대한민국
  • (2008)  Effects of Adult Stem Cell Transplantation in Smoking-Induced Emphysema.  American thoracic society 2008.  캐나다
  • (2007)  BMT regenerates the damaged lungs of rats exposed to cigarette: therapeutic implication of BMCs in chronic obstructive pulmonary disease.  대한약리학회 추계학술대회.  대한민국